Rats rank among the most destructive rodent pests, contaminating stored food grains, causing structural and properties damage and spreading diseases including Lassa fever to both humans and animals. Because rodenticides carry harmful environmental consequences, there’s a clear need to explore alternative control methods that are less damaging to the ecosystem, supporting human safety and protecting food supplies. This study assessed the rodenticidal effects of castor oil seeds on rat stomach histology to control stored product rodent populations. Thirty albino rats (9-10 weeks old) were divided into three replicated groups, each with varying doses of Dichloromethane extract from castor seeds mixed with commercial rat feed. Thirty 9–10-week-old albino rats were divided into three replicated groups with five treatments in each replicate, housing two rats of both sexes per treatment. The rats had unlimited access to food and water. Castor oil seeds were crushed and soaked in Dichloromethane for 24 hours, then extracted and air-dried. The extract was mixed with rat feed in varying doses (200 mg/g, 400 mg/g, 600 mg/g and 800 mg/g of extract to feed) administered to the rats. A control group received only commercial rat feed. The results showed a slight increase in stomach weight (7.12 - 7.50 g) with increasing doses, but no significant difference compared to the control group (6.67). However, histological analysis revealed severe tissue damage in rats treated with the extract, indicating the potential of castor oil seed extract to induce stomach damage in living organisms.